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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '851b4f2293a7dc45d0dd2d443869de6395b2597513b8308fdd99569137d731af' 
  AND token = 'pAvuvy52tS8ADeQZz03JHF1kN+CzFHHCUdEyLjeIIKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}