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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1648bac350c7ad3574ea8b498f076c541740deb6e063dc363faf38a69aad39c' 
  AND token = 'Hql911mboDqDUsB9dicBv3o8RbKs0k7NlHZJPSdqruw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}