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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b2ba1f0639d7b827ca76f0c08cc231487fc4d35192b40d3adaf7b73602da829' 
  AND token = 'KEdL0JlRZwAOVbXr8yV4JhIobR8kBOUVRWXMPMH9tyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}