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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a951fb99bd2fa066dc695a414cd6f8cb4afa33468ade4ecc99ea964deba044' 
  AND token = 'wjW32scOfD4hrT+nkgr2w1085iCdTKrJOzg0YOGyKjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}