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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41a3b07438830797ae89f0b8f53401e34bfed22a20ec88611d4b7965911d03c8' 
  AND token = 'sb8UWRIlmgMwS2lTOEap3mJrUVVC9eiWftyeh+nU7g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}