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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6148abccabacedca33933ce44e9deeb08e77d86582bd10dac46cac84902bf76' 
  AND token = 'g1zEbWJ56SZpLUm4bhKImqq5zczecnBYGb5Tcr0UGSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}