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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87cc769c0737fb9bf805404ad47959c4bbad4e42edcb42b6bf25bed8a30f9573' 
  AND token = '5rWUP3imMYVUpecoJrH0bnaXYCM7SNb0v53qjxvIlcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}