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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd50c9366f4e9bd97652b55ebcb94640340f379a954f217f283171c998c5192ac' 
  AND token = 'fLqgT01N6NbZWP2mYlDYwdcuYF7om3NfEXlxAXU2kk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}