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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dded80f37fe05ec031babaabed4fa004f0b9222a876a4640019b2e3dc0585fe9' 
  AND token = 'aWfcdc65oC32th7PU6vB3ldi0sj+qr4ShTb70PHXG9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}