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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ff7fc62cff9af94e8150252edcbb22e231b7d45dcb770a8bdf1e2e2c50c528' 
  AND token = 'egtsq6AqoZ+pZqqRSNcG0qwQafohjWeGL//eAmJ1k9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}