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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2c710ba6c41d8bf913c67c55a4e8bd6d2ee377da848ff5ebb448dc2966b8f0' 
  AND token = 'RM+rbItJzT+ul7r8Wh3KoO1GFBstKJkAPfg4SI+FFjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}