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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7efb91e4f5b07ab6071012a883f8329124819fa7468535efb14493a8c161d74' 
  AND token = 'HfRUAlH92qsWdlBY7IVulb6QRamvhTNEeGTb5GzRZPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}