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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c808d272e6bdea881b1fc344f76e041a4deab4f7e0d710070dc51f0c30bec8' 
  AND token = 'tN0I1ny1l3vZKEjAEmvVyoD67Iw15KnxDDUOGGV/Geg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}