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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d1829dd0e24df70dd9dde93a94041ad6b13a187f4905245b4f85fa986450f4' 
  AND token = 'oWc69sx+avULdO0EzFMd30B8xh8+UnmO6KRU8IQfUg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}