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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23494ea3567557b8a3657c01aafc7bfb2077b58ad47797b68a56773a15a3a60f' 
  AND token = '+fbDZtNR4LETXs71PL/usk8TF+aUHhdHvFI4DrbCw6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}