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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '283758fd7efcfff1dc92c2e20f8306de6f61078eeb7d1654feea4d8dbdd7ab76' 
  AND token = 'HbHrqTuu3+1u1/PzIr3pnAP6/XCPpkwKLfLbifdtiRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}