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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '014dc3be2e68ec77b332eb2f175b58748f29896ad0080ebf3aed7efbcf528c14' 
  AND token = 'NjCTXnEFFxG/+Bdoza/wu1S9lsPHQx2Hf+WSz94tI6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}