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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '877f134105d2ea830df59c73157ec93e1e83e4ee0961bb168d45057df021b918' 
  AND token = '9j14cubDx0fOZXI+d3w1X8MblZNRbSWHe5CfATvhv3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}