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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7df3a0ba6c0d7612bae2002b474f248a43fc1d5bc14f25445f3654f38dc78484' 
  AND token = '/3X30XnX2FaRl3ryvMCH7awEpSrmMBNVFsSfI510mN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}