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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c19cc76df4e35bccfb562000870ce94c94313a7b420b4e99736cdd8e5a8c0aac' 
  AND token = 'CTIiEhjNYSb+jIDPE8gZtADI4rTHDM5z6sumuAElhc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}