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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8f23fdac7d91b3c27f47beb00ebda1556d366ad177f5d9a6ae86e760c87c952' 
  AND token = 'taETFfRcxJB8TcVnGZmsAIoV+IosCNOQkCVLw9d0siI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}