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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a64bd798b7bb34daedde708a34a0c259bdecb37cbdf8a87424ca88ce7f9e1bb' 
  AND token = 'V1lajkbPXctXbcc+Wb6QhDHs6rzrmtOneXzzbWVQIGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}