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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5792ac1197c67347f1ef98fd701a2c56adfb7c598f4aec26666584a81c7ef165' 
  AND token = 'qvTWIRcmwvR/yaVJDE/ElEAuFXOmGXMtw6RuKSB0EII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}