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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e725422744b6c6c4da6a836a8eeac1ab7b840d9a1419e24db81ded48664d440' 
  AND token = 'ZQMLVyM0VPUsJEWV2f/q5cNHhMitb4g1eECnbVComAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}