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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecaffdf8da08c46482b2093ec4e769b709983e56dfe7a58a1f70cf0a6b24e8aa' 
  AND token = '+YALQ7aRPGRuuTy1+B7Ik/RBy9gDxZCKbWgCduCjrdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}