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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '048095a29e7dd9126ab690804bee108d941c2f12eb647e8e09b377233adb07d3' 
  AND token = 'Z4uJ2f+YzG+VIvKkuAyC5zKM9pm6UIH++u79N2BMIQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}