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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19008cad9a1b118c0e4f42ef219259a5c79bb4be0dded58dcb36f85e1b45e3a8' 
  AND token = '29/LNRMjqYf0je4p6jaldsygatqCVwth3JtMJmnHAxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}