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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2290d90be787e4e4fcac4ae75a5b4aa3900b96a8b6538271b4f88e96ab2c035a' 
  AND token = 'cCXOah2CD43v2xtM3Lgz5I13v+qrxvIlA7dfdsVPvAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}