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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c81b590a0612873b220b357ebbdb37e624cdfbdb3f96ec089308b9f69de5f0d' 
  AND token = 'ZktbcI34M3mXI8YPkjYvGnicF7DbqAulpXi78B2CaDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}