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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48fc28d7a6ac554ad29e96cbb9a22f5abb0bc532931c7071a5796b63976f2eae' 
  AND token = 'dph8xrQNPzHg429SLVgTte+ingtTKhnf4vda5i8/oOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}