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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4a29f58208b300a7fa65bded5b81fbcd54b2e6acc82e8c2f3829ada2f7657b' 
  AND token = 'XdQ/upNAPPGKtnGeAXRDi0hAoEv4W15Wi/5w7jrrwL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}