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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7df7c656d7b70f80b8252816be1d973a64f35b7087e969cabca436f36c404e5' 
  AND token = 'cqE1ktm/XJU8OOCmmGaniw+7AusGit4B+RR+G62dipQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}