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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1649810d5b94a3c9370db065d99d8f96560c65abe27c1f1a66fffc72c03634' 
  AND token = '7TwsZz9emct9kEBoBBTtVeKmNQ1073JCPcsYFhtV4J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}