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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad45a21eb8a1262240b5767644a3a26afdebfca308f792fdbb1aee196ff259ba' 
  AND token = 'lIrLTER5emCHu9AZQEQK4kZNCuf1QpzX77B1iupWll4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}