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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78334dd835965c133f2c1de638c86611431db07fa86867c1cc54ac9a56d12e04' 
  AND token = 'N1IEXRrbmmZg/j0DZEgI3XWnWtEBx/OEFoKMOOxxQ/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}