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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e18bcc3334ab8b820ff149feb7230c3791c7fee37f3187e8b0f9245db14003' 
  AND token = 'aBvkW2tdgp655eAaGj/BTHC230j5CaBaYJPaF46swcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}