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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2754f2e1a7d5fdda8f557c409a903018f00aae355feced7cc7c9994b799ee031' 
  AND token = 'hDUjrlbx/bHA2b+8Yk9PYFJZAM6uaFLcSE7WmOBZ6B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}