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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e70724f72504b7d8b8638a908e5e80ce8c32eb382725a99d441b90603c43fe0e' 
  AND token = 'bNQRw/FSaKRDDiuc58stQczc5nxtVKOVLRw/Xj5LQ5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}