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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33e323af3e0381d50e28453473ce349fa6f36765f60e265c3cfac4b6214d6447' 
  AND token = 'mTDdaQZII6ObRCrCfJfWQVwLJ0srcjL4mg4X0298hPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}