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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cdb6ff7d3f9388bdbba283e2013001738f985fad5f4f5b5195e30cc4673cc1' 
  AND token = '5txG0bLQIvafIp21jV//WDJMswnjbxA0UQw+7MzfJkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}