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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9a8eadce78db07720b8039645c55f63d2386cf2f4777c00783214c2cc1fedf0' 
  AND token = 'AeMM0bbrKLJG2nvt2MI5t0C77aSLcQcl+ZNjrpzI9p8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}