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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6601e966c297b0ecab1e38ad7fc7d87a79db45b6107145e3ffc1ca449a7b13' 
  AND token = 'QCMwNB25AtzKORk6p7ThH07ehZ57Jvg/y5VFdF+15Bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}