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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12e9c6b0a20fa0b37377323bbf71d04b24ceead694348d846238a2bdc805e87b' 
  AND token = 'DqnUaGBWhYAmHGCBfEbDdHfavSL2Q4T/B+nNxXNyieA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}