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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0acde35af1b147d0e93601d8abe134ca3b760ba9b116a2d811d940a76fc1e350' 
  AND token = 'bdu5j6Yi/fly8clpSHXWfJB2t/uixirmdPoenwOlgf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}