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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f04e8b45478a466d40e0263a3a5de9e3ec0bb4ab168c14cd30bd6d7785cc049' 
  AND token = 'Io/ztdni4JG0UPPITgOc/azhhcfmGVeE7bWic5D3B4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}