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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c681aed5e7b72dab9672df7f90e917521b49dc99842059e6f325333f71bea7' 
  AND token = 'rxX2mM8csyyoFFf1MWtggzveE8O1u+IKCnOBC7Ez0R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}