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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f10f05af71c1930e4b0b60cf11a143e70f678d88e21c5e1a68215c24e71d69' 
  AND token = 'C3+ghtKyq5PXNKYFi/SXoVht3TenPenWx/Mjfen1GgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}