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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7eea27f6e7cad3dae8630c49092aff9f646fb302eb29ee20732e965f85198d2' 
  AND token = 'C7jPruF9lw0KfkMEE260O9X/nGc3UBdI2GtFY8cZ7AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}