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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8f01272e5d3a1823a8ce3614833645714c2db7ee3e6c9594a20251d77a9d373' 
  AND token = '7MxCDF69DnfPIGm5VSM57iQt1R48z1eacQq1j2iuW3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}