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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d77a4eed66b3de30c21abfa35d6fd38883f3354f90f43720f13cf9bc82d1327' 
  AND token = 'MiOkE5SLrtp/kqqHLJbgEEtyRGAA+2J4ZLkUOWLTJ3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}